Glutathione is the most important and effective endogenous antioxidant. It is quite simply the body's first line of defense against oxidative stress and a number of xenobiotics (exogenous toxins such as benzenes, heavy metals, and pesticides) which are constantly attacking our cells and enzymes.

With the introduction of Perlingual Glutathione, Supersmart is offering a particularly important, innovative, and world-first supplement – for the first time, it is possible to restore the central element of the body's antioxidant defense system to optimal levels, in a safe and affordable manner.

What are the Benefits of Perlingual Glutathione?

The accumulation of oxidative damage is the most widely accepted biochemical mechanism involved in aging and in the deterioration in physiological function associated with it. There is a direct correlation between aging and decreased intracellular concentrations of glutathione, as well as a strong correlation between increases in these concentrations and improved survival rates. Scientists are now convinced that optimal levels of glutathione are essential for:

• Supporting the immune system;
• Protecting and detoxifying the liver;
• Minimizing the risk of chronic disease;
• Promoting longevity.

Unfortunately, it is difficult and expensive to increase blood levels of glutathione orally. The human intestine contains considerable amounts of an enzyme, gamma-glutamyl transpeptidase, which degrades glutathione as soon as it is ingested.

To date, the only way around this has been to ingest large quantities of glutathione, preferably in combination with other antioxidants which – as much as possible – help maintain it in its reduced state. In this way, at least some glutathione reaches target cells, see our product Reduced Glutathione, but it is a somewhat costly (glutathione is one of the most expensive nutrients) and arbitrary approach. However, human studies have shown that glutathione absorption is significantly increased when it is placed in the mouth, between the cheek and the tongue. In fact, an oral dose of glutathione taken three times a day will restore normal blood and cell levels within a few hours. Perlingual and oral absorption is the fastest, most effective and economic method of administration available.

To increase levels of glutathione in the body, two precursors of this antioxidant are also available from the Supersmart catalogue: N-Acetyl-Cysteine and L-Glutamine. A number of studies have shown that depletion in glutathione may also be reduced by the action of the potent antioxidant R-alpha-lipoic acid. This is often combined in anti-aging medicine with DMAE, an acetylcholine precursor known for its neuroprotective effects.