Hesperidin Methyl Chalcone Supplement for Circulation Support *

Our hesperidin methyl chalcone (HMC) supplement is an extract of Citrus aurantium, standardized to 98%, and delivered in vegetarian capsules. It is designed to help support healthy circulation and vascular function.*

What is Hesperidin Methyl Chalcone?

Hesperidin methyl chalcone is a methylated derivative of the flavonoid hesperidin. It is found in several fruits, particularly citrus fruits. The compound is a pale yellow, slightly bitter, water-soluble powder.

It has been widely used in Japan and Europe as a dietary ingredient and as a component in cosmetic formulations, where it is appreciated for its physicochemical properties and compatibility with products intended for circulation and skin wellness.*

Hesperidin Methyl Chalcone Potential Benefits*

Unlike hesperidin itself, hesperidin methyl chalcone is more water-soluble, which may facilitate its absorption in the gastrointestinal tract. Like many flavonoids, it provides antioxidant compounds that help protect cells from oxidative stress and support overall cellular health.*

Research interest in hesperidin methyl chalcone has focused primarily on its role in supporting vascular integrity and capillary function:*

• Helps support healthy circulation and normal capillary function.*
• Supports leg comfort and a feeling of lightness, particularly after prolonged standing or sitting.*
• Provides antioxidant activity that helps protect tissues from oxidative stress.*
• Is commonly included in formulations designed to support vascular and skin wellness.*

These observations suggest that hesperidin methyl chalcone may contribute to overall circulatory comfort and vascular support when used as part of a balanced lifestyle.*

What Do Studies Explore About HMC?

Several published studies have explored the biological behavior of hesperidin methyl chalcone, particularly in relation to circulation parameters and markers associated with vascular permeability.*

Clinical research has examined its effects on capillary function and fluid balance in healthy volunteers, suggesting a potential role in supporting normal circulatory physiology.*

Additional studies have investigated combinations of hesperidin methyl chalcone with other dietary ingredients, such as citrus flavonoids, plant extracts, and omega-3 fatty acids, to better understand their complementary roles in cellular and metabolic processes.*